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Protonix®

Original price was: $447.28.Current price is: $247.18.

Description

Protonix® Details

Information sourced from the Pfizer Prescribing Information Patient Information. View Patient Information (PDF). Last updated January 25, 2026.

You should take PROTONIX exactly as prescribed, at the lowest dose possible and for the shortest time needed. PROTONIX may help your acid-related symptoms, but you could still have serious stomach problems. Talk with your doctor.

PROTONIX can cause serious side effects, including:

• A type of kidney problem (acute tubulointerstitial nephritis). Some people who take proton pump inhibitor (PPI) medicines may develop a kidney problem that can happen at any time during treatment. Call your doctor right away if you have a decrease in the amount that you urinate or if you have blood in your urine.

• Diarrhea caused by an infection (Clostridium difficile) in your intestines. Call your doctor right away if you have watery stools or stomach pain that does not go away. You may or may not have a fever.

• Bone fractures (hip, wrist, or spine). Bone fractures may happen in people who take multiple daily doses of PPI medicines and for a long period of time (a year or longer). Tell your doctor if you have a bone fracture.

• Certain types of lupus erythematosus. Some people who take PPI medicines may develop certain types of lupus or have worsening of the lupus they already have. Call your doctor right away if you have new or worsening joint pain or a rash on your cheeks or arms that gets worse in the sun.

• Low magnesium and other mineral levels in your body. Can happen in people who have taken PROTONIX for at least 3 months. Tell your doctor if you have symptoms of low magnesium levels, including seizures, dizziness, irregular heartbeat, jitteriness, muscle aches or weakness, and spasms of hands, feet or voice.

PROTONIX is a prescription medicine called a proton pump inhibitor (PPI) used to reduce the amount of acid in your stomach.

In adults, PROTONIX is used for:
• up to 8 weeks for the healing and symptom relief of acid-related damage to the lining of the esophagus (called erosive esophagitis or EE). Your doctor may prescribe another 8 weeks of PROTONIX in patients whose EE does not heal.
• maintaining healing of EE and to help prevent the return of heartburn symptoms caused by GERD. It is not known if PROTONIX is safe and effective when used for longer than 12 months for this purpose.
• the long-term treatment of conditions where your stomach makes too much acid, including Zollinger-Ellison Syndrome.

In children 5 years of age and older, PROTONIX is used for:
• up to 8 weeks for the healing and symptom relief of EE. It is not known if PROTONIX is safe if used longer than 8 weeks in children.

PROTONIX is not for use in children under 5 years of age.

• are allergic to pantoprazole sodium, any other PPI medicine, or any of the ingredients in PROTONIX. See the end of this leaflet for a complete list of ingredients.
• are taking a medicine that contains rilpivirine (EDURANT, COMPLERA, ODEFSEY, JULUCA) used to treat HIV-1.
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